Author

A. Fridrich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Assay:bulk RNA-seq· 4 Organism:non-human primate· 4 Research Focus:development & morphogenesis· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Y. Moran· 7 shared R. Aharoni· 4 shared J. M. Surm· 3 shared A. M. Tripathi· 2 shared K. Sunagar· 2 shared M. Lewandowska· 2 shared M. Salinas-Saavedra· 2 shared U. Frank· 2 shared

Activity by Year

2017-2023 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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7 shared papersEvolutionary Biology

Y. Moran

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7 papers

Recent·Most cited

Venom tradeoff shapes interspecific interactions, physiology and reproduction

J. M. Surm, S. J. Birch, J. Macrander, A. Jaimes-Becerra, A. Fridrich, R. Aharoni, R. Rozenblat, J. Sharabany, L. Appelbaum, A. M. Reitzel, Y. Moran

This study shows that reducing Nv1 toxin levels in sea anemones decreases predator defense but increases growth and reproductive rates, revealing a venom tradeoff.

bioRxiv · Jul 24, 2023Evolutionary Biology

Target complementarity in cnidarians supports a common origin for animal and plant microRNAs

Y. Admoni, A. Fridrich, T. Razin, M. Salinas-Saavedra, M. Rabani, U. Frank, Y. Moran

The paper investigates miRNA-target complementarity in cnidarians, showing they require full complementarity for silencing, similar to plants, and differ from bilaterians.

bioRxiv · Jan 8, 2023 · PreprintEvolutionary Biology

A pan-cnidarian microRNA is an ancient biogenesis regulator of stinging cells

A. Fridrich, M. Salinas-Saavedra, I. Kozlovski, J. M. Surm, E. Chrysostomou, A. M. Tripathi, U. Frank, Y. Moran

The paper identifies miR-2022 as a conserved microRNA essential for cnidocyte biogenesis across cnidarian species.

bioRxiv · Dec 15, 2022Evolutionary Biology

Functional characterization of a "plant-like" HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

A. M. Tripathi, Y. Admoni, A. Fridrich, M. Lewandowska, J. M. Surm, R. Aharoni, Y. Moran

The paper shows that a HYL1 homolog in Nematostella vectensis is essential for miRNA biogenesis and development, suggesting an ancestral miRNA system in animals and plants.

bioRxiv · May 31, 2020Evolutionary Biology

Unravelling the developmental and functional significance of an ancient Argonaute duplication

A. Fridrich, V. Modepalli, M. Lewandowska, R. Aharoni, Y. Moran

The paper investigates the role of miRNAs and their Argonaute paralogs in the sea anemone Nematostella vectensis, revealing new insights into miRNA evolution and function outside bilaterians.

bioRxiv · Feb 4, 2020Evolutionary Biology

Dynamics of venom composition across a complex life cycle

Y. Y. Columbus-Shenkar, M. Y. Sachkova, A. Fridrich, V. Modepalli, K. Sunagar, Y. Moran

The paper investigates venom composition changes across developmental stages in Nematostella vectensis using transcriptomic and biochemical methods, revealing dynamic shifts linked to ecological differences.

eLife · Feb 9, 2018Peer-reviewedEvolutionary Biology

Cell type-specific expression profiling sheds light on the development of a peculiar neuron, housing a complex organelle

K. Sunagar, Y. Columbus-Shenkar, A. Fridrich, N. Gutkovitch, R. Aharoni, Y. Moran

The paper characterizes cell-type specific transcriptomes of cnidocytes in Nematostella vectensis, revealing gene expression shifts during cnidocyst maturation and novel transcription factor involvement.

bioRxiv · Jun 30, 2017Evolutionary Biology