Truncated titin is integrated into the human dilated cardiomyopathic sarcomere
D. Kellermayer, H. Tordai, B. Kiss, G. Török, D. M. Peter, A. A. Sayour, M. Polos, I. Hartyanszky, B. Szilveszter, S. Labeit, A. Gango, G. Bedics, C. Bödör, T. Radovits, B. Merkely, M. Kellermayer
The paper investigates TTNtv mutations in DCM by analyzing cardiac samples, finding truncated titin integrated into sarcomeres with structural defects.
bioRxiv · Feb 8, 2023 · PreprintBiophysics