The carboxyl-terminal processing proteases Prc and CtpA modulate cell-surface signalling activity and Pseudomonas aeruginosa virulence
J. R. Otero-Asman, A. Sanchez-Jimenez, K. C. Bastiaansen, S. Wettstadt, C. Civantos, A. Garcia-Puente, W. Bitter, M. Llamas
This study identifies CtpA as a protease that modulates CSS activation and virulence in Pseudomonas aeruginosa by regulating the anti-{sigma} factor, with implications for drug development.
bioRxiv · Mar 13, 2023 · PreprintMicrobiology