ZNF827 pleiotropic cardiovascular risk locus involves regulation by Nuclear factor-1
Y. Liu, L. Liu, A. Esmael, M.-A. Fustier, A. Georges, N. Bouatia-Naji
This paper identifies rs13128814 as the causal variant at the ZNF827 locus linked to SCAD, CAD, and cardiovascular traits, showing it regulates ZNF827 expression via NF1 transcription factor binding.
bioRxiv · Jan 23, 2024 · PreprintCell Biology