Author

A. Gorfe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Hoang· 1 shared J. Selvakumar· 1 shared K. Arumugam· 1 shared K. M. Rehl· 1 shared K. M. Sepuru· 1 shared K. Rajarathnam· 1 shared K.-J. Cho· 1 shared P. Prakash· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

D. Hoang

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2 papers

Recent·Most cited

A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95.

K. M. Rehl, J. Selvakumar, D. Hoang, K. Arumugam, A. Gorfe, K.-J. Cho

This study shows a ferrocene derivative inhibits K-Ras function by oxidative modification at His95, blocking its membrane binding and signaling in cancer cells.

bioRxiv · Mar 28, 2023 · PreprintCell Biology

Long-range coupled motions underlie ligand recognition by a chemokine receptor

K. Rajarathnam, K. M. Sepuru, V. Nair, P. Prakash, A. Gorfe

This study investigates how Site-I interactions in CXCR1 contribute to ligand recognition by CXCL8 through structural plasticity, using NMR and MD simulations.

bioRxiv · Jul 28, 2020Biophysics