Author

A. Graffeuil

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Microbiology· 1

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

B. E. Uhlin· 1 shared D. A. Cisneros· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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1 shared paperMicrobiology

B. E. Uhlin

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1 paper

Recent·Most cited

Polar mutagenesis of bacterial transcriptional units using Cas12a

A. Graffeuil, B. E. Uhlin, D. A. Cisneros

The paper demonstrates that Cas12a can efficiently engineer polar mutations in the fim operon of E. coli, disrupting gene expression and showing potential for transcriptional shutdown in metabolic engineering.

bioRxiv · Feb 21, 2020 · PreprintMicrobiology