Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state
A. Maiti, A. Hedger, W. Myint, V. Balachandran, J. Watts, C. A. Schiffer, H. Matsuo
The paper determines the structure of APOBEC3G bound to a DNA inhibitor, revealing the transition state geometry and providing insights for inhibitor design.
bioRxiv · Aug 15, 2022Biochemistry