Single molecule tracking the uncoupling of assembly and membrane insertion in Perfringolysin O
M. J. Senior, C. Monico, E. E. Weatherill, R. Gilbert, A. Heuck, M. I. Wallace
This study uses single-molecule tracking to reveal the assembly and membrane insertion pathway of Perfringolysin O, showing stepwise irreversible assembly with monomer addition.
bioRxiv · May 26, 2021Biophysics