Clusterin in Alzheimer's disease: an amyloidogenic inhibitor of amyloid formation
P. M. Spatharas, G. I. Nasi, P. L. Tsiolaki, M. K. Theodoropoulou, N. C. Papandreou, A. Hoenger, I. P. Trougakos, V. A. Iconomidou
This study identifies aggregation-prone regions in clusterin and shows they can form amyloid-like fibrils and inhibit amyloid-beta fibril formation.
bioRxiv · Apr 2, 2021Biophysics