Author

A. Holoubek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:multiome· 1

Frequent Co-Authors

B. Brodska· 3 shared D. Grebenova· 3 shared K. Kuzelova· 3 shared A. Obr· 2 shared P. Otevrelova· 2 shared D. Strachotova· 1 shared M. Sasinkova· 1 shared P. Herman· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

B. Brodska

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3 papers

Recent·Most cited

Group I p21-activated kinases in leukemia cell adhesion to fibronectin

K. Kuzelova, A. Obr, P. Roselova, D. Grebenova, P. Otevrelova, B. Brodska, A. Holoubek

This study investigates the role of PAK group I kinases in leukemia cell adhesion to fibronectin, showing differential effects of PAK inhibitors on cell behavior and survival.

bioRxiv · Aug 25, 2020Cell Biology

NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization

M. Sasinkova, P. Herman, A. Holoubek, D. Strachotova, P. Otevrelova, D. Grebenova, K. Kuzelova, B. Brodska

The paper shows that NSC348884 does not inhibit NPM oligomerization but instead affects cell adhesion signaling, leading to cytotoxicity in leukemia cells.

bioRxiv · Feb 6, 2020Cell Biology

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions

D. Grebenova, A. Holoubek, P. Röselova, A. Obr, B. Brodska, K. Kuzelova

This study compares PAK1, PAK1Δ15, and PAK2, showing PAK1Δ15 is more similar to PAK2 than PAK1-full in localization and function, with distinct roles in cell adhesion and glycolysis.

bioRxiv · Mar 18, 2019Cell Biology