The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
J. Lavie, C. Lalou, W. Mahouf, J.-W. Dupuy, A. Lacaule, A. Ars, D. Lacombe, A.-M. Duchene, A.-A. Raymond, H. R. Rezvani, P. Ngondo, G. Benard
This study identifies FBXL6 as a regulator of mitochondrial ribosomal protein quality during cytosolic translation, showing its role in preventing aggregation and maintaining mitochondrial function.
bioRxiv · Nov 1, 2022Cell Biology