J.-W. Dupuy

This study shows that blocking CXCR4 improves lung and cardiac outcomes in early COPD using both human samples and mouse models.

The paper identifies Rnd3 loss as inducing entosis in hepatocellular carcinoma, with LAMP1 playing a key role in the process and correlating with metastatic potential.

This study identifies FBXL6 as a regulator of mitochondrial ribosomal protein quality during cytosolic translation, showing its role in preventing aggregation and maintaining mitochondrial function.

The paper investigates interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammation, showing increased proximity and functional effects in COPD patients.

This study shows DDR2 drives melanoma drug resistance via AXL-dependent phenotype switching, suggesting DDR inhibition as a potential second-line treatment.

This study shows that UDP-glucose pyrophosphorylase (UGP) is imported into glycosomes by piggybacking on phosphoenolpyruvate carboxykinase (PEPCK) and that both cytosolic and glycosomal UGP pathways are functional in trypanosomes.

The paper shows that a deletion event between FRDg and FRDm2 genes is selected in PEPCK knockout cells, leading to a non-functional chimeric gene that reduces growth, suggesting FRD's role in ROS production for parasite differentiation.

This study identifies genes and proteins up-regulated in Botrytis cinerea infection cushions, revealing their role in plant penetration and other functions like camouflage and necrotrophy.