The autophagy initiating kinase ULK1 is required for pancreatic cancer cell growth and survival
R. J. Shaw, S. N. Brun, J. Lumibao, A. Limpert, H. Ren, A. Ianniciello, N. Cosford, H. Tiriac, M. Downes, R. Evans, D. D. Engle
This study shows ULK1 is essential for pancreatic cancer cell growth and survival, and ULK1 inhibitors can enhance immunotherapy by increasing MHC Class I expression.
bioRxiv · May 15, 2021 · PreprintCancer Biology