Chromatin organization drives the exploration strategy of nuclear factors
M. Mazzocca, A. Loffreda, E. Colombo, T. Fillot, D. Gnani, P. Falletta, E. Monteleone, S. Capozi, E. Bertrand, G. Legube, Z. Lavagnino, C. Tacchetti, D. Mazza
This study shows how nuclear factors explore chromatin by balancing diffusion and dense region sampling, with implications for p53 function and nuclear organization.
bioRxiv · Dec 29, 2022 · PreprintBiophysics