Theoretical analysis predicts an optimal therapeutic strategy in distinct parkinsonian landscapes of the striatum
M. L. Heltberg, H. N. Awada, A. Lucchetti, M. H. Jensen, J. K. Dreyer, R. N. Rasmussen
The paper uses biophysical modeling to analyze denervation patterns in the striatum and identifies an optimal cellular strategy for maintaining dopamine signaling in Parkinson's disease.
bioRxiv · Jul 19, 2020 · PreprintBiophysics