Author

A. M. Block

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. D. Tischler· 2 shared S. B. Namugenyi· 2 shared A. M. Brokaw· 1 shared K. B. Beckman· 1 shared L. Zhang· 1 shared N. P. Palani· 1 shared P. C. Wiegert· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

A. D. Tischler

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2 papers

Recent·Most cited

Mycobacterium tuberculosis requires conditionally essential metabolic pathways for infection

A. M. Block, P. C. Wiegert, S. B. Namugenyi, A. D. Tischler

This paper identifies metabolic pathways essential for Mycobacterium tuberculosis survival during infection using transposon sequencing in a mouse model, highlighting Phe and purine/thiamine biosynthesis as potential drug targets.

bioRxiv · Sep 6, 2023Microbiology

Mycobacterium tuberculosis requires the outer membrane lipid phthiocerol dimycocerosate for starvation-induced antibiotic tolerance

A. M. Block, S. B. Namugenyi, N. P. Palani, A. M. Brokaw, L. Zhang, K. B. Beckman, A. D. Tischler

This paper identifies phthiocerol dimycocerosate (PDIM) as essential for Mycobacterium tuberculosis antibiotic tolerance under nutrient starvation, suggesting PDIM synthesis as a target to enhance antibiotic efficacy.

bioRxiv · Jul 7, 2022Microbiology