Author

A. M. Downing

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Biology Disciplines

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Biochemistry· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Ramkumar· 1 shared D. W. Nowakowski· 1 shared H. Bodin· 1 shared J. Castro· 1 shared K. M. Ori-McKenney· 1 shared M. M. Rogers· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Ramkumar

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1 paper

Recent·Most cited

Autoregulatory control of microtubule binding in the oncogene, doublecortin-like kinase 1

M. M. Rogers, A. Ramkumar, A. M. Downing, H. Bodin, J. Castro, D. W. Nowakowski, K. M. Ori-McKenney

This study identifies autophosphorylation as a mechanism regulating DCLK1 kinase activity and microtubule binding affinity, offering insights into its role in cancer.

bioRxiv · Jun 12, 2020 · PreprintBiochemistry