The major role of sarA in limiting Staphylococcus aureus extracellular protease production is correlated with decreased virulence in diverse clinical isolates in osteomyelitis
M. J. Campbell, K. E. Beenken, A. M. Ramirez, M. S. Smeltzer
This study shows that sarA mutation reduces virulence in S. aureus osteomyelitis by increasing protease production, highlighting its key role in limiting protease output and maintaining virulence.
bioRxiv · Nov 7, 2022 · PreprintMicrobiology