Insights into stereoselective ring formation in canonical strigolactone: Discovery of a dirigent domain-containing enzyme catalyzing orobanchol synthesis
M. Homma, T. Wakabayashi, Y. Moriwaki, N. Shiotani, T. Shigeta, K. Isobe, A. Okazawa, D. Ohta, T. Terada, K. Shimizu, M. Mizutani, H. Takikawa, Y. Sugimoto
This study identifies a dirigent domain-containing enzyme, SRF, that catalyzes the stereoselective BC-ring closure in orobanchol biosynthesis, revealing the molecular mechanism for SL stereochemistry.
bioRxiv · Aug 7, 2023 · PreprintPlant Biology