Mucosal vaccination for SARS-CoV-2 elicits superior systemic T central memory function and cross-neutralizing antibodies against variants of concern
A. ONeill, M. P. Kala, C. W. Tan, W. A. A. Saron, C. K. Mantri, A. P. S. Rathore, L.-F. Wang, A. L. St. John
This study shows that intranasal vaccination with SARS-CoV-2 S-RBD and mucosal adjuvant M7 enhances T central memory cells and cross-neutralizing antibodies against variants of concern compared to subcutaneous vaccination.
bioRxiv · Sep 9, 2022 · PreprintImmunology