Cancer BiologyNature CommunicationsPeer-reviewed
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
E. G. Alvarez, J. Demeulemeester, C. Jolly…·J. Tubio
The paper identifies a mutational mechanism in hepatocellular carcinoma driven by Hepatitis B virus DNA integration, leading to genomic restructuring and oncogenic rearrangements.
DOI 10.1038/s41467-021-26805-8