Machine Learning based histology phenotyping to investigate epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits
Craig A. Glastonbury, Sara L. Pulit, Julius Honecker, Jenny C. Censin, Samantha Laber, Hanieh Yaghootkar, Nilüfer Rahmioğlu, Emilie Pastel, Katarina Kos, A. Pitt, Michelle Hudson, Christoffer Nellåker, Nicola L. Beer, Hans Hauner, Christian Malte Becker, , Cecilia M. Lindgren
The paper develops a deep learning method for adipocyte phenotyping and finds adipocyte area correlates with BMI but no genome-wide significant genetic associations.
PLoS Computational Biology · Aug 14, 2020Peer-reviewedGenomics