Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer
M. J. Williams, M. U. Oliphant, V. Au, C. Liu, C. Baril, C. O'Flanagan, D. Lai, S. Beatty, M. Van Vliet, J. C. Liu, L. O'Connor, W. L. Goh, A. Pollaci, A. C. Weiner, D. Grewal, , S. Aparicio
The paper analyzes copy number alterations in breast epithelial cells from BRCA mutation carriers and wildtype individuals, finding lineage-specific CNAs that mirror cancer genomes.
bioRxiv · May 1, 2024 · PreprintCancer Biology