Author

A. Rosace

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Bennett· 1 shared C. Poulsen· 1 shared L. I. Sakhnini· 1 shared M. M. Mortensen· 1 shared M. Oeller· 1 shared N. Lorenzen· 1 shared P. Sormanni· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Bennett

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1 paper

Recent·Most cited

Automated optimisation of solubility and conformational stability of antibodies and proteins

A. Rosace, A. Bennett, M. Oeller, M. M. Mortensen, L. I. Sakhnini, N. Lorenzen, C. Poulsen, P. Sormanni

This study introduces an automated computational method to co-optimize solubility and conformational stability of antibodies, validated on six antibodies with improved developability without affecting antigen-binding.

bioRxiv · May 20, 2022Biochemistry