IL-7-adjuvanted vaginal vaccine elicits strong mucosal immune responses in non-human primates
S. Logerot, S. Figueiredo, B. Charmeteau, A. Sandouk, A.-S. Drillet-Dangeard, M. Bomsel, I. Bourgault-Villada, A. Couedel-Courteille, R. Cheynier, M. Rancez
This study shows that IL-7-adjuvanted vaginal vaccination in macaques enhances mucosal immune responses by promoting chemokine expression, immune cell infiltration, and tertiary lymphoid structure formation.
bioRxiv · Nov 9, 2020Immunology