Author

A. Sastokas

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Evolutionary Biology· 1

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Approach:experimental assay· 1 Organism:yeast· 1

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D. Newell· 1 shared G. Kinsler· 1 shared K. Geiler-Samerotte· 1 shared K. Schmidlin· 1 shared S. Apodaca· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperEvolutionary Biology

D. Newell

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1 paper

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Evolutionary BiologybioRxivOct 17, 2023

Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs

K. Schmidlin, S. Apodaca, D. Newell…·K. Geiler-Samerotte

The paper identifies distinct fitness tradeoff groups among fluconazole-resistant yeast mutants, suggesting different resistance mechanisms and implications for multidrug therapy design.

DOI 10.7554/elife.94144

yeastexperimental assay