Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs
K. Schmidlin, S. Apodaca, D. Newell, A. Sastokas, G. Kinsler, K. Geiler-Samerotte
The paper identifies distinct fitness tradeoff groups among fluconazole-resistant yeast mutants, suggesting different resistance mechanisms and implications for multidrug therapy design.
bioRxiv · Oct 17, 2023Evolutionary Biology