Biguanide-PROTACs: Modulating Mitochondrial Proteins in Pancreatic Cancer Cells
J. Vatte, V. Bourdeau, G. Ferbeyre, A. Schmitzer
This study synthesizes Biguanide-PROTACs and evaluates their activity on pancreatic cancer cells, finding structure-permeability-activity relationships and some AMPK activation.
bioRxiv · Mar 17, 2024 · PreprintCancer Biology