Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth
A. Seel, F. Padovani, A. Finster, M. Mayer, D. Bureik, C. Osman, T. Klecker, K. M. Schmoller
The paper shows that mitochondrial DNA copy number increases with cell volume in budding yeast through nuclear-encoded factors, maintaining stable concentrations without cell-cycle regulation.
bioRxiv · Dec 3, 2021Cell Biology