Switching metalloporphyrin binding specificity of a b-type cytochrome to fluorogenic zinc by design
B. J. Bowen, A. R. McGarrity, A. Szeto, C. Pudney, D. Jones
The paper designs a cytochrome variant that switches metalloporphyrin binding specificity from iron to zinc protoporphyrin IX, significantly enhancing its fluorescence.
bioRxiv · Nov 6, 2019Biochemistry