Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH
M. R. Swiatnicki, J. P. Rennhack, D. Hollern, A. V. Perry, R. Kubiak, S. M. Riveria Riveria, S. O'Reilly, E. R. Andrechek
This paper shows that PTPRH mutations in NSCLC lead to elevated EGFR phosphorylation, which can be targeted by existing EGFR inhibitors.
bioRxiv · Sep 14, 2021Cancer Biology