The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities
E. Estebanez-Perpina, A. Jimenez-Panizo, A. Alegre-Marti, G. Fettweis, M. Abella, R. Anton, T. Tettey, L. R. Schiltz, T. A. Johnson, I. Nunez-Barrios, J. Font-Diaz, C. Caelles, A. Valledor, P. Perez, A. M. Rojas, , P. Fuentes-Prior
This study identifies non-canonical dimerization modes of the glucocorticoid receptor ligand-binding domain through structural analysis and functional assays.
bioRxiv · Oct 1, 2021Biochemistry