P. Perez

SARS-CoV-2 Infection of Salivary Glands Compromises Oral Antifungal InnateImmunity and Predisposes to Oral Candidiasis

This study shows SARS-CoV-2 infection reduces histatin-5 in salivary glands, impairing antifungal immunity and increasing Candida albicans prevalence in COVID-19 patients.

Polybacterial intracellular coinfection of epithelial stem cells in periodontitis

This study identifies polybacterial intracellular co-infection in human periodontal epithelial cells, revealing its proinflammatory effects and potential role in chronic diseases.

ABLs and TMKs are co-receptors for extracellular auxin

The paper identifies ABL1 and ABL2 as new auxin receptors that function with TMKs as co-receptors for extracellular auxin, overlapping with but distinct from ABP1.

Myosin II regulatory light chain phosphorylation and formin availability modulate cytokinesis upon changes in carbohydrate metabolism.

This study shows that RLC phosphorylation and formin availability regulate cytokinesis in fission yeast during respiration.

Stress-dependent inhibition of cell polarity through unbalancing the GEF/GAP regulation of Cdc42

The paper shows that oxidative stress inhibits Cdc42 activity at cell poles via Sty1 kinase, leading to reduced cell polarity and elongated morphology in fission yeast.

The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities

This study identifies non-canonical dimerization modes of the glucocorticoid receptor ligand-binding domain through structural analysis and functional assays.

Removal of the C6 vaccinia virus interferon-β inhibitor in the hepatitis C vaccine candidate MVA-HCV elicited in mice high immunogenicity in spite of reduced host gene expression

The paper describes a modified HCV vaccine candidate, MVA-HCV ΔC6L, which lacks an IFN-β inhibitor and shows strong immunogenicity in mice despite reduced host gene expression.