MerTK mediates the immunologically silent uptake of alpha-synuclein fibrils by human microglia
M.-F. Dorion, K. Senkevich, M. Yaqubi, N. W. Kieran, C. X.- Q. Chen, A. MacDonald, W. Luo, A. Wallis, I. Shlaifer, J. Hall, R. W. R. Dudley, I. A. Glass, Birth Defects Research Laboratory, J. A. Straton, E. A. Fon, , L. M. Healy
This study shows MerTK mediates microglial uptake of alpha-synuclein fibrils without triggering inflammation and links MERTK variants to Parkinson's disease.
bioRxiv · Mar 4, 2023 · PreprintCell Biology