Pharmacology & ToxicologybioRxiv
Conjugates for use in peptide therapeutics: a systematic review and meta-analysis
A. Wijesinghe, S. Kumari, V. Booth
This paper reviews and analyzes conjugates that extend therapeutic peptide half-life, finding glycosaminoglycans and engineered peptides offer significant improvements over PEGylation.
DOI 10.1371/journal.pone.0255753