Loss of the Ap4A hydrolase YqeK impairs stress adaptation and virulence gene expression in Staphylococcus aureus
J. Vidaud, J.F. Coker, J. Silva, G.S. Davidson, C.C. Anderson, G.M. Bassett, A.A. Harry, T. Dusenbury, T.M. Gardner, M.L. Melear, N.J. Moraga, J.D. Fender, Caitlin M. McMahon, Melinda R. Grosser
This paper shows that loss of YqeK in S. aureus increases stress sensitivity and reduces virulence gene expression, suggesting YqeK as a target for anti-virulence drugs.
Journal of Bacteriology · Aug 20, 2026Peer-reviewedMicrobiology