Identification of a convergent spinal neuron population that encodes itch
Tayler D. Sheahan, Charles A. Warwick, Abby Cui, David A. A. Baranger, Vijay J. Perry, Kelly M. Smith, Allison P. Manalo, Eileen K. Nguyen, H. Richard Koerber, Sarah E. Ross
The paper identifies a GRPR-expressing spinal neuron population that encodes itch and shows that kappa opioid receptor agonists inhibit itch by targeting these neurons.
bioRxiv · Sep 29, 2023 · PreprintNeuroscience