SOX2-VSX2 Co-Occupancy Shapes Retinal Neurogenesis Through Dynamic Chromatin Regulation
Fuyun Bian, Kimiasadat Golestaneh, Emily Davis, Abdullah Khan, Marwa Daghsni, Keevon Flohr, Silvia Liu, Susana da Silva, Len A. Pennacchio, Issam Aldiri
This study identifies SOX2 and VSX2 co-occupancy in retinal progenitor cells and shows how their cooperative binding regulates chromatin accessibility and neurogenesis.
bioRxiv · May 19, 2025 · PreprintDevelopmental Biology