Author

Abigail Bennington

Manchester Academic Health Science Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Catherine B. LawrenceiD· 2 shared Frances Hedley· 2 shared Paul R. KasheriD· 2 shared Víctor S. TapiaiD· 2 shared Adam El Khouja· 1 shared Anna van der Zwaluw· 1 shared Basudha BasuiD· 1 shared Christopher HoyleiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Catherine B. LawrenceORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prpf8N1531S homozygous mutant mouse embryos have multiple defects in cardiac development and show aberrant splicing of the cardiac transcription factor Tead1

Wasay Mohiuddin Shaikh Qureshi, Haoxiang Zhou, Abigail Bennington, Nouf J. Althali, Anna van der Zwaluw, Michael Boylan, Louise A. Stephen, Kashish Jain, Basudha Basu, Dapeng Wang, Colin A. Johnson, Kathryn E. Hentges

This study identifies a critical role for Prpf8 in cardiac development through aberrant splicing of Tead1 and disrupted Notch signaling in Prpf8N1531S homozygous mutant mice.

bioRxiv · Apr 21, 2026 · PreprintDevelopmental Biology

Vascular dilation modulates brain haematoma expansion in larval zebrafish

Víctor S. Tapia, Tom Hardy, Daisy Flatman, Abigail Bennington, Frances Hedley, Poornima Geemon, Catherine B. Lawrence, Paul R. Kasher

This study shows that vascular dilation reduces haematoma size in zebrafish ICH models, suggesting haemodynamic regulation influences haemorrhage progression.

bioRxiv · Mar 28, 2026 · PreprintCell Biology

25-hydroxycholesterol promotes brain endothelial dysfunction by remodelling cholesterol metabolism

Víctor S. Tapia, Sarah E. Withers, Ran Zhou, Abigail Bennington, Christopher Hoyle, Frances Hedley, Adam El Khouja, Nadim Luka, Marco Massimo, Siobhan Crilly, Katherine R. Long, Catherine B. Lawrence, Paul R. Kasher

The paper shows that 25-hydroxycholesterol disrupts brain endothelial function by altering cholesterol metabolism, linking viral infection to brain vessel dysfunction in intracerebral haemorrhage.

Disease Models & Mechanisms · May 23, 2025Peer-reviewedNeuroscience