zebrafish

Endothelial protein C receptor is an entry receptor for Langya virus

This study identifies the endothelial protein C receptor (EPCR) as the entry receptor for Langya virus and reveals the molecular basis of its interaction with the viral attachment glycoprotein.

Disparities in avian genomic resources highlight gaps across the Global South

The paper evaluates avian genome assemblies across geography and taxonomy, revealing underrepresentation of species in the Global South.

Quantitative live imaging reveals region-dependent medulloblastoma disseminationin the zebrafish brain

This study uses live imaging in zebrafish to show that hindbrain medulloblastoma cells spread more frequently than forebrain or midbrain tumors and that dasatinib reduces dissemination.

Plumage diversity without differential expression of pigmentation genes in a rapid avian radiation

The paper investigates plumage diversity in Capuchino Seedeaters by analyzing gene expression and variants, finding that pigmentation differences arise from regulatory changes rather than differential gene expression.

Signatures for conserved phenolic-based acclimation responses to UV in a unicellular algal sister of land plants

The paper exposes zygnematophyte algae to UV irradiance and identifies conserved molecular responses, including lipid droplets and phenolic compounds, suggesting a shared UV acclimation mechanism with land plants.

Regenerative epithelial spike cells instruct immune niche homeostasis in zebrafish fin epidermis

The paper identifies a novel epithelial cell type in zebrafish fins, spike cells, and shows their role in maintaining immune cell niche homeostasis through interactions with mpeg1+ immune cells.

Genomic architecture of the major histocompatibility complex genes in the Neotropical Midas cichlid

This study characterizes the MHC genomic architecture in the Midas cichlid using integrated genomic and transcriptomic analyses, revealing gene diversity, evolutionary patterns, and tissue-specific expression.

Mapping the regulatory wiring of endothelial cell differentiation reveals a critical role for Hippo mechanosignaling

The paper maps gene regulators of endothelial cell differentiation using CRISPR and single-cell RNA-seq, identifying Hippo mechanosignaling as critical for endothelial identity.

Light-dependent conversion of body color change pattern during zebrafish development

This study shows that light exposure during rearing induces a developmental switch in zebrafish body color response to light, independent of pineal photoreceptors.

Genome-wide chromatin accessibility during early embryogenesis in a generalist cichlid fish

This study maps genome-wide chromatin accessibility in A. calliptera embryos across three stages, revealing dynamic changes in regulatory elements and transcription factor activity during early development.

Hidden infections: Linking parasite ecology, fish health and stakeholder perceptions in Nile tilapia aquaculture in central Kenya

The paper investigates parasite infections in Nile tilapia aquaculture, finding that monopisthocotylan parasites are prevalent and linked to gill lesions, while stakeholders rarely identify parasites as a health cause.

Rapid Electro-optic Two-photon Bessel Light Sheet Fluorescence Lifetime Imaging for Tissue Volume Interrogation

This paper introduces a new two-photon fluorescence lifetime imaging technique for rapid volumetric imaging of biological samples with high resolution and low phototoxicity.

Structural and evolutionary insights into FcαμR recognition of polymeric immunoglobulins

This study determines cryo-EM structures of FcR bound to IgM and IgA, revealing its binding mechanism and evolutionary insights into pIg receptor recognition.

Parallel and lineage-dependent mitonuclear evolution in threespine stickleback

This study examines parallel evolution of nuclear OXPHOS genes in threespine stickleback across freshwater populations and identifies mitonuclear evolutionary coupling in specific functional modules.

Basal ganglia output guides decision-making by state destabilization

The paper shows that basal ganglia output in zebrafish destabilizes neural activity states to guide decision-making in a Go/No-go task.

Apelin signaling controls neuroendocrine homeostasis via Atoh8-dependent transcriptional regulation

This study shows Apelin signaling regulates neuroendocrine homeostasis in zebrafish via Atoh8-dependent transcriptional control, affecting development, fertility, and aging.

Removal of maternal compensation reveals retinal-specific roles for Pomgnt1 in zebrafish

This study shows that removing maternal compensation in zebrafish reveals retinal-specific roles for Pomgnt1, with retinal abnormalities appearing early and behavioral changes observed.

DPYD links glial lipids and myelination to sleep duration

This study identifies DPYD's role in sleep regulation through glial lipid metabolism and myelination across species, linking genetic variants to oligodendrocyte-specific control.

Reaction-time asymmetry covaries with shifts in hand choice in macaques

This study shows that macaque hand choice and reaction time are influenced by target position, hand displacement, head rotation, and gaze direction, similar to human behavior.

Resonant Recognition Model analysis of cGAS: conserved spectral frequencies and a divergent naked mole-rat phase signature

This paper uses the Resonant Recognition Model to analyze cGAS and FANCI sequences across species, identifying conserved spectral features and divergent phase signatures in naked mole-rats.

Marked Mutants Allow for Rapid Non-Invasive Genotyping of Zebrafish by Visual Inspection Alone

This paper introduces a method to rapidly genotype zebrafish mutants using visual inspection by inserting fluorescent markers into target genes, enabling non-invasive identification of genotypes.

Hmox1/CO regulates retina regeneration via modulation of Wnt/β-catenin signalling and induction of vaspb in zebrafish

This study identifies Hmox1/CO as a regulator of zebrafish retina regeneration through Wnt/β-catenin signaling and vaspb induction, with implications for mammalian regeneration.

Comparative Oogenesis in Annual and Non-annual African Killifishes: Oocyte Staging in the Fastest-Aging Vertebrate, Nothobranchius furzeri

This study compares oogenesis in annual and non-annual killifishes, finding conserved developmental stages but divergent zona pellucida features in the annual species.

Unpredictable chronic stress redistributes novelty-evoked exploratory space use and yields method-dependent identification of resilient-like archetypes in zebrafish

This study shows UCS in zebrafish alters exploratory behavior patterns, with method-dependent identification of resilient-like archetypes.

Deep-intronic variants in USH2A: the importance of model selection in variant interpretation and pathogenicity assessment

The paper evaluates two USH2A variants using minigene assays and zebrafish models, finding that one variant may be benign and the other not pathogenic.

Establishing an assay for visual desensitization in larval zebrafish for understanding synaptic plasticity

This study develops an assay in larval zebrafish to investigate visual desensitization and its role in synaptic plasticity by measuring escape responses to varying visual stimuli.

Unfamiliar conspecifics increase freezing and shift movement towards immobility in zebrafish, most clearly in males

This study shows that unfamiliar conspecifics increase freezing and shift movement towards immobility in zebrafish, particularly in males, and elevate cortisol levels overall.

Human and zebrafish data corroborate gene x gene interactions in ameliorating Duchenne muscular dystrophy disease progression

The paper investigates gene-gene interactions in Duchenne muscular dystrophy using human and zebrafish data, finding interaction effects for six gene pairs and rescue of muscle organization in zebrafish for MAN1A1 and ACTN3.

A multi-tissue RNA-seq atlas of adult medaka (Oryzias latipes) under salinity and winter-summer sampling contrasts

The paper generates a multi-tissue RNA-seq atlas of adult medaka under salinity and seasonal contrasts to study gene-expression plasticity and comparative biology.

Coding region changes in the Hippo pathway component YAP1 contribute to body size differences among mammalian species

This study identifies coding region changes in YAP1 that contribute to body size differences among rodents by showing increased growth-promoting activity in capybara YAP1 compared to mouse and vole YAP1.