Author

Aboubakar Sako

Novo Nordisk Foundation

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Brianna M. LaxiD· 1 shared Charlotte Held GotfredseniD· 1 shared Christopher K. WeingarteniD· 1 shared Daniela RagoiD· 1 shared David Harding-LarseniD· 1 shared Ditte Hededam WelneriD· 1 shared Kasper Enemark‐RasmusseniD· 1 shared Manuel Nieto‐DomíngueziD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Brianna M. LaxORCID

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2 papers

Recent·Most cited

BioengineeringChem & Bio EngineeringPeer-reviewedAug 5, 2026

Data-efficient distal engineering of fluorinase using zero-shot models

David Harding-Larsen, Brianna M. Lax, Christopher K. Weingarten…·Ditte Hededam Welner

This study uses zero-shot models to predict activity-enhancing mutations in fluorinase, leading to improved catalytic efficiency and stability in engineered variants.

DOI 10.1021/cbe.6c00028

protein sequencedeep learning

Synthetic BiologybioRxivPreprintNov 28, 2023

High-yield enzymatic synthesis of mono- and trifluorinated alanine enantiomers

Manuel Nieto‐Domínguez, Aboubakar Sako, Kasper Enemark‐Rasmussen…·Pablo I. Nikel

This study develops an enzymatic method to produce fluorinated alanine enantiomers with high yield and enantiomeric excess.

DOI 10.1101/2023.11.28.569005

experimental assay