Author

Adam Ruppert

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jordan B. MetziD· 1 shared Jun Yang· 1 shared Mayra Marquez· 1 shared Qian Chen· 1 shared Tomozumi ImamichiiD· 1 shared Udeshika KariyawasamiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Jordan B. MetzORCID

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1 paper

Recent·Most cited

IL-27 Reduces Cell-Surface LDLR in Human Macrophages and Restricts VSV-G-Pseudotyped HIV infection

Qian Chen, Udeshika Kariyawasam, Mayra Marquez, Jordan B. Metz, Jun Yang, Adam Ruppert, Tomozumi Imamichi

This study shows IL-27 reduces cell-surface LDLR in macrophages and limits VSV-G-pseudotyped HIV infection through receptor downregulation and post-entry mechanisms.

bioRxiv · Oct 28, 2026 · PreprintImmunology