Jun Yang

IL-27 Reduces Cell-Surface LDLR in Human Macrophages and Restricts VSV-G-Pseudotyped HIV infection

This study shows IL-27 reduces cell-surface LDLR in macrophages and limits VSV-G-pseudotyped HIV infection through receptor downregulation and post-entry mechanisms.

Scene Structure Predicts Perceptual Decisions in Naturalistic Detection Tasks

This study shows that perceptual decisions in natural scenes are influenced by background context, with texture entropy and edge density as key features, supported by psychophysics, AR, DNNs, and EEG.

The P3018S disease variant reveals how dynein's trailing motor sets ensemble velocity.

The paper investigates how the P3018S mutation in dynein affects its function, revealing that the trailing motor in multi-dynein assemblies dictates ensemble velocity.

A cerebellar cognitive rheostat bidirectionally controls attention

This study identifies a cerebellar circuit that bidirectionally controls attention by suppressing sensorimotor noise and amplifying cognitive signals, with implications for ADHD.

Inactivating a β1 subunit of SnRK1 promotes broad-spectrum disease resistance in rice

This study shows that disrupting the SnRK1β1A gene in rice confers broad-spectrum resistance to fungal diseases without affecting growth or yield.

RIPK1 Biallelic Activating Variants lead to Autoinflammatory Disease Driven by T cell Death

This study identifies biallelic RIPK1 activating variants causing autoinflammatory disease through T cell death and cytokine amplification.

UDP-glucose:anthocyanidin 3-O-glucoside-2”-O-glucosyltransferase catalyzes further glycosylation of anthocyanins in purple Ipomoea batatas

This study identifies Ib3GGT as a UDP-glucose-dependent anthocyanin 3-O-glucoside-2”-O-glucosyltransferase in purple sweetpotato, revealing its role in anthocyanin glycosylation and the importance of Thr-138 in UDP-glucose recognition.