Author

Adan Horta

Mortimer B. Zuckerman Mind Brain Behavior Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Daniele CanzioiD· 3 shared Rachel DuffiéiD· 3 shared Stavros LomvardasiD· 3 shared Hani J. ShayyaiD· 2 shared Kevin D. MonahaniD· 2 shared Marko JovanoviciD· 2 shared Martín Escamilla-Del-ArenaliD· 2 shared Sandy M. RajkumariD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersGenomics

Daniele CanzioORCID

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Author profile →

4 papers

Recent·Most cited

HP1B and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity

Martín Escamilla-Del-Arenal, Rachel Duffié, Hani J. Shayya, Valentina Loconte, Axel A. Ekman, Lena Annika Street, Adan Horta, Daniele Canzio, Kevin Monahan, Carolyn Larabell, Marko Jovanovic, Stavros Lomvardas

This study shows that HP1β regulates olfactory receptor choice and neuronal identity in mice by modulating H3K9me3 levels and chromatin structure, leading to changes in OR expression patterns and reduced receptor diversity.

International Journal of Molecular Sciences · Mar 24, 2026Peer-reviewedMolecular Biology

Stemness factor Mex3a times translation and protein trafficking to ensure robust differentiation of olfactory sensory neurons

Martín Escamilla-Del-Arenal, Lauren C. Tang, Albana L. Kodra, Hani J. Shayya, Aileen Ugurbil, Olga Stathi, Abdurrahman Keskin, Adan Horta, Joan Pulupa, Junqiang Ye, Marko Jovanović, Stavros Lomvardas, Rachel Duffié

This study shows that Mex3a regulates neuronal differentiation by controlling translation and trafficking of cell surface proteins, cilia structure, and planar cell polarity in olfactory sensory neurons.

bioRxiv · Feb 9, 2026 · PreprintGenetics

Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring

Lea Alice Kiefer, Gabrielle Isabelle F. Servito, Sandy M. Rajkumar, Jennifer Langen, Anna Chiosso, Alexander Buckley, S. Elizabeth, Adan Horta, Michael H. Mui, Daniele Canzio

The paper reveals cohesin's role in enabling stochastic Protocadherin expression in olfactory sensory neurons by regulating enhancer-promoter interactions and DNA demethylation, contrasting with deterministic expression in serotonergic neurons.

bioRxiv · Mar 9, 2022 · PreprintGenomics

Antisense lncRNA transcription drives stochastic Protocadherin α promoter choice

Daniele Canzio, Chiamaka L. Nwakeze, Adan Horta, Sandy M. Rajkumar, Eliot L. Coffey, Erin E. Duffy, Rachel Duffié, Kevin D. Monahan, Sean O’Keeffe, Matthew D. Simon, Stavros Lomvardas, Tom Maniatis

The paper shows antisense lncRNA transcription is required for stochastic Protocadherin promoter choice in neurons.

Cell · Apr 1, 2019Peer-reviewedGenomics