Developmental BiologybioRxivPreprint
Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis
Nicole A. Edwards, Scott A. Rankin, Adhish Kashyap…·Aaron M. Zorn
The paper shows that disruptions in endosomal trafficking of the Vangl-Celsr polarity complex cause congenital trachea-esophageal malformations in Xenopus, similar to human EA/TEF.