Author

Adrian Chan

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Christoph DieterichiD· 2 shared Anne-Maud FerreiraiD· 1 shared Carolin P. M. ScheitliD· 1 shared Chiara Krämer· 1 shared Claudia HöbartneriD· 1 shared Dirk GrimmiD· 1 shared Emerald Perlas· 1 shared Isabel S. Naarmann‐de VriesiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Christoph DieterichORCID

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Author profile →

2 papers

Recent·Most cited

mAFiA: Detecting m6A at single-molecular resolution via direct-RNA sequencing

Adrian Chan, Isabel S. Naarmann‐de Vries, Carolin P. M. Scheitl, Claudia Höbartner, Christoph Dieterich

The paper develops a method to detect m6A modifications at single-molecular resolution using direct-RNA sequencing by creating synthetic data and a bespoke algorithm.

bioRxiv · Jul 28, 2023 · PreprintBioinformatics

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy

Markus Grosch, Laura Schraft, Adrian Chan, Leonie Küchenhoff, Kleopatra Rapti, Anne-Maud Ferreira, Julia Kornienko, Shengdi Li, Michael H. Radke, Chiara Krämer, Sandra Clauder‐Münster, Emerald Perlas, Johannes Backs, Michael Gotthardt, Christoph Dieterich, , Lars Michael Steinmetz

This study uses base editors and AAVMYO to correct Rbm20 mutations in cardiomyocytes, improving splicing and cardiac function in mouse models of dilated cardiomyopathy.

Nature Communications · Jun 22, 2023Peer-reviewedGenetics