A first insight into the developability of an IgG3: A combined computational and experimental approach
Georgina Bethany Armstrong, Alan Lewis, Vidhi Shah, Paul Taylor, Craig Jamieson, Glenn A. Burley, William Lewis, Zahra Rattray
This study characterizes the developability of IgG3 mAbs using computational and experimental methods, finding poorer stability and higher viscosity compared to IgG1.
ACS Pharmacology & Translational Science · Jul 15, 2024Peer-reviewedBioengineering