Craig Jamieson

The paper shows that breast cancer micrometastases alter metabolism to change extracellular vesicle production, creating an invasive microenvironment.

This study characterizes the developability of IgG3 mAbs using computational and experimental methods, finding poorer stability and higher viscosity compared to IgG1.

This study presents a framework for computationally screening mutations to modify antibody viscosity, showing that hydrophobic and electrostatic patches significantly affect viscosity, with positive charges causing the most increase.

This study evaluates a type IV ATX inhibitor, Cpd17, showing improved efficacy over a type I inhibitor in reducing liver injury in mouse models of acute liver injury and non-alcoholic steatohepatitis.