Persistent Malignant Stem Cells Drive Relapse After Transplantation in the Myelodysplastic Neoplasms
Benjamin R. Kroger, Roni Tamari, Carmelo Gurnari, Yuanyuan Ji, Yazan F. Madanat, Yi Huang, Reiko Tachibana, Toby Thomas, Albert Son, Peter Carlsgaard, Clayton W. Jackson, Vivian Irizarry-Gatell, Alejandro Mariños, Zachary Brady, Prapti Arvind Patel, , Stephen S. Chung
The paper detects malignant hematopoietic stem cells (HSCs) in myelodysplastic neoplasms (MDS) using low-input sequencing and shows they predict relapse after transplantation.
bioRxiv · Oct 29, 2026 · PreprintCancer Biology