Alexander D. Friedman

This study shows that A2A-positive neurons in the NAc core regulate effort exertion by bidirectional modulation of lever pressing behavior in an effort-dependent manner.

This study selectively stimulates STN projection neurons in mice and shows that STN output directly controls movement parameters with high precision.

This study shows that VTA dopamine neurons bidirectionally control impulse vector and anticipatory behavior during motivated actions.

This study investigates the roles of striatonigral and striatopallidal pathways in action performance and timing using optogenetic stimulation in mice.